Assistant Professor, Biology
- Ph.D., Biochemistry, Dartmouth College, Hanover, NH, 2004
Thesis title: The Effects of Niemann-Pick Type C Disease in the Central Nervous System - In Vitro and In Vivo Analyses of Neuronal Function
- Non-matriculating graduate studies, Rutgers University, Camden, NJ, 1996-1997
- B.S., Biology, LaSalle University, Philadelphia, PA, 1995
- Dartmouth Medical School, Department of Biochemistry, 1998-2004
- BioPure Corporation, Souderton, PA, 1995-1998
Quality Control Analyst
- Visiting Assistant Professor of Biology, Pine Manor College, 2008-present
Courses taught include BI101: Principles of Biology Lecture and Lab, BI205: Anatomy and Physiology Lecture and Lab, BI206: Anatomy and Physiology lecture (co-taught) and lab
- Visiting Assistant Professor, Fitchburg State College, Summer 2009
Taught General Biology I lecture and lab in Summer session I
- Assistant Professor of Biology, Division of Natural Sciences and Mathematics, St. Thomas Aquinas College, 2005-2008
Courses taught include Bio 100: Current Issues in Biology, Bio 101: Human Biology, Bio 140: Marine Biology, Bio 201/211/202/212: General Biology Lecture and Lab, Bio 300: Neuroscience, Bio 306: Genetics, Bio 400: Independent study on the Biology of Alzheimer’s Disease, Bio 403/Chem 403: Biochemistry
- Visiting Assistant Professor of Biology, Division of Natural Sciences and Mathematics, St. Thomas Aquinas College, 2004-2005
- Teaching Assistant, Department of Biological Sciences, Dartmouth College, 2000-2001
Courses taught include Bio3: Human Biology and Bio16: Introduction to Genetics
- Pine Manor College:
- Curriculum Committee
- Integrated Advising Team (IAT)
- Quantitative Reasoning Committee
- Co-Advisor to the Science Club
- St. Thomas Aquinas College
- Middle States Subcommittee
- First Year Seminar Committee
- Library and Information Resources Committee
- Advisor to the Biology Club
- Dartmouth College
- Student Representative to the Graduate committee
Fellowships and Awards
- Albert J. Ryan Fellowship, 2001-2002
- Paul C.A., Jarvinen M.K., Boegle A.K., Fry W.M., Yang P., Penatti C.A., Henderson L.P., and Maue R.A. The role of synaptic input and intrinsic excitability in the development of aberrant electrical activity in Purkinje neurons during Niemann-Pick Type C disease (In preparation).
- Paul C.A. and Maue, R.A. Adenoviral-mediated delivery and expression of an NPC1-GFP fusion gene improves the progression of NPC disease (In preparation)
- Paul C.A., Boegle A.K., Reid P.C., Zhang M.A., Blanchette-Mackie J., Karten B. Liscum L., Vance J.E., Chang T.-Y., and Maue R.A. Adenovirus expressing an NPC1-GFP fusion gene corrects neuronal and nonneuronal defects associated with Niemann pick type C disease. Journal of Neuroscience Research, 81 (5): 706-719, 2005.
- Paul C.A., Boegle A.K., and Maue R.A. Before the Loss: Neuronal dysfunction in Niemann-Pick Type C Disease. Biologica and Biophysica Acta, 1685 (1-3): 63-76, 2004
- Henderson LP, Lin L, Prasad A, Paul CA, Chang TY, Maue RA. Embryonic striatal neurons from Niemann-Pick Type C mice exhibit defects in cholesterol metabolism and neurotrophin responsiveness. Journal of Biological Chemistry, 275(26):20179-87, 2000.
- Paul CA, Boegle, AK, Reid PC, Karten B, Liscum L, Vance JE, Chang TY, and Maue RA. The utilization of an adenovirus expressing an NPC1-GFP fusion gene to correct Niemann-Pick Type C disease deficiencies in vitro and in vivo. Soc. Neurosci. Abstr. 33rd Annual Meeting, New Orleans, LA, 2003
- C.A. Paul, M.K. Jarvinen, D.M. Porter, A. Prasad, L. Lin, and R.A. Maue. Neuronal Membrane Signaling in Niemann-Pick Type C Disease. Soc. Neurosci. Abstr., 31st Annual Meeting, San Diego, CA, 2001.
- Paul CA, Boegle, AK, Reid PC, Karten B, Liscum L, Vance JE, Chang TY, and Maue RA. Development of an adenovirus expressing an NPC1-GFP fusion gene with functional effects in vitro and in vivo. International Conference on Niemann-Pick Type C Disease 2003.